The Shared Platform for Antibiotic Research and Knowledge (SPARK)

One of the barriers to discovering new antibiotics is a lack of information sharing. Despite a long history of antibiotic research, scientists often cannot build on past work, or avoid repeating mistakes, because research findings are scattered across the academic literature or not publicly available. The field has also experienced a significant brain drain, losing years of experience as industry research-and-development teams have downsized or shifted to other therapeutic areas. And to make matters worse, the science itself—finding molecules that can break through the defenses of the toughest bacteria—is very difficult. 

To help address these challenges, Pew created the Shared Platform for Antibiotic Research and Knowledge (SPARK), a cloud-based, virtual laboratory that enables scientists to share data and insights, learn from past research, and generate new insights into how molecules enter and stay inside of Gram-negative bacteria. Using technology developed by Collaborative Drug Discovery, Inc., SPARK integrates chemical and biological data from published studies as well as previously unpublished data, and provides an opportunity for real-time collaboration among scientists in industry, academia, government, and the nonprofit sector.

Similar data-sharing tools have successfully catalyzed drug discovery in other research areas, such as cancer, neglected tropical diseases, and tuberculosis. Pew hopes that SPARK will do the same for antibiotic-resistant bacteria.

Request Access to SPARK

SPARK (Shared Platform for Antibiotic Research and Knowledge) is a publicly-available, cloud-based information-sharing tool to help spur antibiotic discovery. SPARK is available to users at no cost.

What SPARK helps scientists do
• Share data and insights
• Learn from past research
• Generate new insights into how molecules enter and stay inside of Gram-negative bacteria

How SPARK works
Using technology developed by Collaborative Drug Discovery, Inc., SPARK integrates chemical and biological data from published and unpublished work. The tool enables real-time collaboration among scientists in industry, academia, government, and the nonprofit sector.

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Read SPARK Terms of Use

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I have read and agree to the SPARK Terms of Use and Privacy Policy

Your Information


I understand that by registering for SPARK, my name and email address will be shared with Pew and Pew’s third-party host of the SPARK Platform (Collaborative Drug Discovery, Inc.). I also understand that my name will be accessible to any other SPARK user, and that certain functionality on SPARK may allow those users to send me messages within the platform. I consent to the collection, use, and disclosure of my information in accordance with the SPARK Platform Terms of Use, the Pew Charitable Trusts Privacy Policy, and the Privacy Policy of the SPARK Platform host.